Category: Medicine

All details in attached file (Research proposal Note).
Second published research For your information its research with same idea for my needs maybe helping you .

Step 1: In a one to two-page paper, give an overview of the embryonic stage of development.

-Describe the ectoderm, mesoderm, and endoderm and their associated structures.
-Discuss the structure and function of the embryonic disk.
-Describe embryo development and the role of chorionic villi.
-Include any environmental factors that may cause malformations in the developing embryo.

Describe your cultural views of pregnancy.
•Describe how a pregnant woman is viewed and treated by society
•Discuss what beliefs are held about the biological processes occurring with regards to her body.
•Include what the perception of the developing fetus may be.
•Discuss what preparations are made for the upcoming labor, delivery, and birth.
•Include how impending parenthood is anticipated.

Effect of Binge eating (long term, short term on individual aspects and community aspects )
Each of u write 200 to 250 words with minimum 5 references (last 5 years ) from Major sources like PubMed, WHO, CDC etc
Note: Evaluation will be done based on content, references and plagiarism free and quality of English

1 Scenario 1: Myocardial Infarction
CC: “I woke up this morning at 6 a.m. with numbness in my left arm and pain in my chest. It feels tight right here (mid-sternal).” “My dad had a heart attack when he was 56-years-old and I am scared because I am 56-years-old.”
HPI: Patient is a 56-year-old Caucasian male who presents to Express Hospital Emergency Department with a chief complaint of chest pain that radiates down his left arm. He states this started this morning and has been getting worse, pointing to the mid-sternal area, “it feels like an elephant is sitting on my chest and having a hard time breathing”. He rates the pain as 9/10. Nothing has made the pain better or worse. He denies any previous episode of chest pain. Denies nausea, or lightheadedness. Nitroglycerin 0.4 mg tablet sublingual x 1 which decreased pain to 7/10.
Lipid panel reveals Total Cholesterol 424 mg/dl, high density lipoprotein (HDL) 26 mg/dl, Low Density Lipoprotein (LDL) 166 mg/dl, Triglycerides 702 mg/dl, Very Low-Density Lipoprotein (VLDL) 64 mg/dl
His diagnosis is an acute inferior wall myocardial infarction.
Question:
Which cholesterol is considered the “good” cholesterol and what does it
2 Scenario 1: Myocardial Infarction
CC: “I woke up this morning at 6 a.m. with numbness in my left arm and pain in my chest. It feels tight right here (mid-sternal).” “My dad had a heart attack when he was 56-years-old and I am scared because I am 56-years-old.”
HPI: Patient is a 56-year-old Caucasian male who presents to Express Hospital Emergency Department with a chief complaint of chest pain that radiates down his left arm. He states this started this morning and has been getting worse, pointing to the mid-sternal area, “it feels like an elephant is sitting on my chest and having a hard time breathing”. He rates the pain as 9/10. Nothing has made the pain better or worse. He denies any previous episode of chest pain. Denies nausea, or lightheadedness. Nitroglycerin 0.4 mg tablet sublingual x 1 which decreased pain to 7/10.
Lipid panel reveals Total Cholesterol 424 mg/dl, high density lipoprotein (HDL) 26 mg/dl, Low Density Lipoprotein (LDL) 166 mg/dl, Triglycerides 702 mg/dl, Very Low-Density Lipoprotein (VLDL) 64 mg/dl
His diagnosis is an acute inferior wall myocardial infarction.
Question:
1. How does inflammation contribute to the development of atherosclerosis?
3 Scenario 2: Pleural Friction Rub
A 35-year-old female with a positive history of systemic lupus erythematosus (SLE) presents to the Emergency Room (ER) with complaints of sharp retrosternal chest pain that worsens with deep breathing or lying down. She reports a 5-day history of low-grade fever, listlessness and says she feels like she had the flu. Physical exam reveals tachycardia and a pleural friction rub. She was diagnosed with acute pericarditis.
Question:
1. Because of the result of a pleural friction rub, what does the APRN recognize?
Scenario 4: Deep Venous Thrombosis (DVT)
A 81-year-old obese female patient who 48 hours post-op left total hip replacement. The patient has had severe nausea and vomiting and has been unable to go to physical therapy. Her mucus membranes are dry. The patient says the skin on her left leg is too tight. Exam reveals a swollen, tense, and red colored calf. The patient has a duplex ultrasound which reveals the presence of a deep venous thrombosis (DVT).
Question:
1. Given the history of the patient explain what contributed to the development of a deep venous thrombosis (DVT)
Scenario 5: COPD
A 66-year-old female with a 50 pack/year history of cigarette smoking had a CT scan and was diagnosed with emphysema. He asks if this means he has chronic obstructive pulmonary disease (COPD).
Question:
1. There is a clear relationship between emphysema and COPD, explain the pathophysiology of emphysema and the relationship to COPD.
CARDIOVASCULAR AND RESPIRATORY DISORDERS
In this exercise, you will complete a 5-essay type question Knowledge Check to gauge your understanding of this module’s content.
Possible topics covered in this Knowledge Check include:
myocardial infarction
endocarditis
myocarditis
valvular disorders
lipid panels
coagulation
clotting cascade
deep vein thrombosis
hypertension
heart failure
COPD
asthma
pneumonias

Please write methodology according to STROBE checklist and based on the following introduction, aims and objectives as well as data collection questionnaire questions .
Celiac Disease (CD) is a genetically predisposed autoimmune disorder marked by a unique serological and histological profile that is brought on by consuming gluten (1). The term “gluten”
refers to a group of proteins that are alcohol-soluble and found in a variety of grains, such as wheat, rye, barley, spelt, and kamut (1). The primary clinical manifestations include extra-intestinal symptoms like anemia, dermatitis herpetiformis, peripheral neuropathy, and osteopenia as well as intestinal symptoms like diarrhea, abdominal distension, and discomfort(2). Patients with CD are treated with a gluten-free diet (GFD) for the rest of their lives.
Continued use of gluten can worsen clinical symptoms, cause more intestinal damage, and raise the risk of developing cancers in the future, such as non-Hodgkin’s lymphoma, esophageal cancer, small intestinal adenocarcinoma, and melanoma(3) However, severe diet compliance involves significant abandonments and lifestyle adjustments that have a negative impact on the overall quality of life (QoL)(4)
A study that is the first and only meta-analysis on the prevalence of CD in Saudi Arabia states that (1.4%) of people have a biopsy-proven CD (5). The “Classic type” of CD marked by malabsorption and gastrointestinal symptoms, is less common than the atypical form, which is frequently asymptomatic and involves extra-intestinal clinical signs, therefore CD is usually ill-defined (6).
The diagnosis of CD should be supported by three main findings: a clinical examination, a small intestinal histopathologic examination, and an examination for serum markers. Important diagnostic tools for celiac disease include oral signs and symptoms such as tooth enamel hypoplasia, oral ulcers, and pain or burning in the tongue.(7)
The field of CD serological testing has advanced significantly in recent years. endomysial antibodies (EMA), Antigliadin antibodies (AGA), and tissue transglutaminase antibodies (tTG) are the most often employed antibodies (8). Early 1980s saw the development of the AGA test, but more current assays may have greater sensitivities and particularities than the now-outdated AGA. In comparison to EMA and tTG test findings, the recently developed deamidated gliadin peptide antibody (DGP) has demonstrated promising performance. However, the information and experience about DGP use are still developing (8)
Some researchers reported that CD was associated with different oral manifestations in children, and the most common oral symptom was Dental enamel defects. Recurrent aphthous stomatitis, multiple caries, delayed dental eruption, and other oral signs that are also linked to celiac disease(9).
The most typical ulcerative condition affecting the oral mucosa is recurrent aphthous stomatitis (RAS). It generally affects healthy people but can also appear clinically in immunocompromised people differently. Numerous local, systemic, immunologic, genetic, allergy, dietary, and microbiological variables, as well as immunosuppressive medications, have been identified as potential causes of RAS, but its exact cause is still unknown. (10)
To the best of the authors’ knowledge, the data regarding celiac disease in the Kingdom of Saudi Arabia is limited, so the present study is prop
Research aim and objectives
Investigate the epidemiological characteristics, pathological features, and clinical manifestations of Celiac Disease in Children and Adults.
To assess the treatment and management approaches and investigate the long-term impact of celiac diseases on oral health.

OUTBREAK REPORT QUESTIONS:
1. List 4 critical questions you should ask sick individuals in order to describe the illness and begin to figure out the cause of the disease outbreak.
2. Give at least 3 ways you could investigate the outbreak that could help you decide the cause and how to stop disease spread (Examples: Survey of sick patients? Data from medical care sources? Site visit?) Give 1 advantage or disadvantage for each approach.
3. Determining how rapid and intense your investigation needs to be is a critical part of any outbreak investigation. Identify at least 3 criteria to help you decide how urgent the response to a probable food-borne disease outbreak like this should be.
4. Identify an epidemiologic study design that would likely clarify the origin of the outbreak.
5. Describe 3 methods to stop this kind of food borne outbreak.
Instructions and example are added
Book access VitalSource (the burden of diseases)

This is a very general research-like paper. This paper will be written about Amyloid Protein (including Amyloid-Beta Protein, and Amyloid Precursor Protein). The paper should be 4 pages, double-spaced, and written using proper APA formatting. Please include APA-style in-text citations and a reference page constructed in APA format. This paper only needs 5 sources all of which must be peer-reviewed articles from the databases I will link in the uploaded file.
Things to include in the writing:
– what are Amyloid Protein, Amyloid-Beta Protein, and Amyloid Precursor Protein?
– how or why do these proteins misfold
– Amyloid plaques/ Neurofibrillary tangles
– how does Amyloid Protein in all forms play role in Neurodegenerative diseases I.e Alzheimer’s, and Dementia?

An understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity.
Effective disease analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial and ethnic variables all can have an important impact.
An understanding of the signals and symptoms of alterations in cellular processes is a critical step in the diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate patients and guide them through their treatment plans.
In this Assignment, you examine a case study and analyze the symptoms presented. You identify cell, gene, and/or process elements that may be factors in the diagnosis, and you explain the implications to patient health.
RESOURCES
Be sure to review the Learning Resources before completing this activity.
Click the weekly resources link to access the resources.
WEEKLY RESOURCES
To prepare:
By Day 1 of this week, you will be assigned to a specific case study for this Case Study Assignment. Please see the “Announcements” section of the classroom for your assignment from your Instructor.
The Assignment
Develop a 1- to 2-page case study analysis in which you:
Explain why you think the patient presented the symptoms described.
Identify the genes that may be associated with the development of the disease.
Explain the process of immunosuppression and the effect it has on body systems.
BY DAY 7 OF WEEK 2
Submit your Case Study Analysis Assignment by Day 7 of Week 2.
Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at https://academicguides.waldenu.edu/writingcenter/templates Links to an external site.). All papers submitted must use this formatting.
SUBMISSION INFORMATION
Before submitting your final assignment, you can check your publish for authenticity. To check your publish, access the Turnitin publishs from the Start Here area.
To submit your completed assignment, save your Assignment as MD1Assgn_LastName_Firstinitial
Then, click on Start Assignment near the top of the page.
Next, click on Upload File and select Submit Assignment for review.

Rubric

What has been your most humbling experience and how will that experience affect your interactions with your peers and patients?