Category: Pharmacology

Using the attached research article, complete the attached worksheet.
And then create a 2 page summary essay based on the worksheet. The summary essay has to be in paragraph form, that I will read in front of class.

The unapproved use of approved drugs, also called off-label use, with children is quite common. This is because pediatric dosage guidelines are typically unavailable, since very few drugs have been specifically researched and tested with children.
When treating children, prescribers often adjust dosages approved for adults to accommodate a child’s weight. However, children are not just “smaller” adults. Adults and children process and respond to drugs differently in their absorption, distribution, metabolism, and excretion.
Children even respond differently during stages from infancy to adolescence. This poses potential safety concerns when prescribing drugs to pediatric patients. As an advanced practice nurse, you have to be aware of safety implications of the off-label use of drugs with this patient group.
Review the interactive media piece in this week’s Resources and reflect on the types of drugs used to treat pediatric patients with mood disorders.
Reflect on situations in which children should be prescribed drugs for off-label use.
Think about strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Consider specific off-label drugs that you think require extra care and attention when used in pediatrics.
Write a 1-page narrative in APA format that addresses the following:
Explain the circumstances under which children should be prescribed drugs for off-label use. Be specific and provide examples.
Describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Include descriiptions and names of off-label drugs that require extra care and attention when used in pediatrics.
ex: zoloft , paxil, wellbutrin
APA 7th format
3 sources between the years 2017-2023

Your patient presents to the emergency department with a chief complaint of headaches, fatigue, and not sleeping well. Your patient describes the headaches as a dull ache generalized throughout with a lack of interest in usual activities. Symptoms began approximately three weeks ago, and progressively been getting worse. The past medical history includes depression and psychosis (diagnosed at age 23). When asked about alcohol intake and current prescriptions, it was reported three red-bull with vodka’s are consumed every night, smokes ½ a pack of cigarettes per day, and admits to not being compliant with medications. You note some concerning behaviors including delusions, disassociation, and difficulty focusing on the conversation. Your patient also admits to feeling sad almost all the time with thoughts of hopelessness and worthlessness (denies suicidal ideation). Current prescriptions
Fluphenazine 30 mg PO every day
Venlafaxine 225 mg PO every day
Tylenol (Acetaminophen) 650 mg PRN for headaches
Directions
You will need to include the following elements into your case study. Please don’t upload your case study as an attachment, rather directly into the discussion board. List the interactions found by going to the following link https://reference.medscape.com/drug-interactionchecker (Links to an external site.) and checking the medications the patient is prescribed to assess for any interactions
List concerns with the interactions, medications, and treatment plan
List a minimum of (5) recommendations to prevent any adverse events
Respond to (1) colleague speaking to their recommendations, something you weren’t aware of, or any recommendations for your colleague.
Cite all your sources in APA (this includes in-text citations and a reference list). Anytime you are using content that is not your own, a citation is needed
You should utilize your textbook, but can also utilize any additional resources you find
Follow the rubric to guide you, which can be found by clicking on the 3 dots in the right upper quadrant of the screen
Review the case study example as to how to format and speak to each category

Answer the questions below based on the following case study.
A 41-year-old man presents to his PCP with feelings of hopelessness, sadness, and helplessness. He says that he cries for no reason, and has difficulty sleeping. He noticed that the problems began about 6 weeks before, and he did not feel able to shrug them off. He has been drinking more alcohol than usual and has stopped going to work. When on his own, he admitted that he had thought of driving his car into the nearest canal.
Summarize the clinical case.
What is the DSM 5-TR diagnosis based on the information provided in the case?
Which pharmacological treatment would you prescribe including the name, dose, route and frequency of the drug in accordance with the clinical guidelines? Include the rationale for this treatment.
Which non-pharmacological treatment would you prescribe according to the clinical guidelines? Include the rationale for this treatment excluding a psychotherapeutic modality.
Include an assessment of the treatment’s appropriateness, cost, effectiveness, safety, and potential for patient adherence to the chosen medication. Use a local pharmacy to research the cost of the medication and provide the most cost-effective choice for the patient. Use great detail when answering questions 3-5.
Submission Instructions:
Your initial post should be at least 500 words, formatted and cited in the current APA style with support from at least 2 academic sources. Your initial post is worth 8 points.

There are two separate questions. Please say if you chose yes or no for each question. 110 words each

I need reasons of why a drug that work as an inhibitor of IL-17 will work on Emphysema not on Chronic bronchitis. Please include your citation and highlights the paragraphs used of the articles used. Thank you.

AC is a 72-year-old male who is admitted to your ICU after suffering a massive stroke that has left him unresponsive and unable to communicate. He is currently on a ventilator. His wife of 48 years is available along with their one adult daughter. The wife informs you that they don’t have any advanced directives, but she is “pretty sure her husband would not want to live like this.” However, their daughter is adamant her dad would want to be kept alive in case there is any chance to come out of this.
Explain the ethical and legal implications of the scenario you selected on all stakeholders involved, such as the prescriber, pharmacist, patient, and patient’s family.
Describe strategies to address disclosure and nondisclosure as identified in the scenario you selected. Be sure to reference laws specific to your state.
Explain two strategies that you, as an advanced practice nurse, would use to guide your decision making in this scenario, including whether you would disclose your error. Be sure to justify your explanation.
Explain the process of writing prescriptions, including strategies to minimize medication errors.

Write a 2- to 3-page paper that addresses the following:
Explain the ethical and legal implications of the scenario you selected on all stakeholders involved, such as the prescriber, pharmacist, patient, and patient’s family.
Describe strategies to address disclosure and nondisclosure as identified in the scenario you selected. Be sure to reference laws specific to your state.
Explain two strategies that you, as an advanced practice nurse, would use to guide your decision making in this scenario, including whether you would disclose your error. Be sure to justify your explanation.
Explain the process of writing prescriiptions, including strategies to minimize medication errors.

Jayden is a 27-year-old male who presents for evaluation of treatment of ADD/HD. He was diagnosed for the first time in adolescence and has been on medication on and off ever since. He has been off medication for a few years but now has a job that really emphasizes his symptoms, and he needs pharmacotherapy. Assume that he meets diagnostic criteria for ADD, mixed type. What medications will you prescribe for him, and why?
Write a prescriiption for him and discuss why you selected one drug class over the others.

Which strategy works for you and which one does not? Elaborate on the reason why do you think they work on you.
Requirements:
Minimum 2 page paper not counting the title page
References not required
Minimum 500 words